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Sample Size: 200mL
Cooling: Jacketed
Dimensions: 13cm×13cm×9cm
Weight: 2kg
Min. Sample Size: 10mL
Application: Liposome formulation up to production scale; Sterile filtration
Max. Pressure: 1,500 psi-6,000 psi
Temp. Limit: 80ºC (176ºF)
Power Type: High pressure pump or high pressure homogenizer
Nano-membrane: Track-etched membrane
Cleaning: Flush to clean/CIP/SIP
Sterilization: Whole unit autoclavable
Standard Features
Parts
1) Liposome Online Extruder
2) 10 pieces of 100nm membrane
Filter Support: Jacketed filter support with pagoda inlet and outlet
Inlet Type: UNF 1/4" high pressure coupling for GOE-25ml/200ml/1L
Outlet Type: UNF 1/4" high pressure coupling for GOE-25ml/200ml/1L
Handle: Handle for GOE-800mL, GOE-3000mL and GOE-10000mL
Nano Membrane: 100nm track-etched polycarbonate membrane
Compatibility: Some parts are compatible with Lipex in Northern Lipids
Product Material: 316L stainless steel, viton
Material Standard: Sanitary grade; compliant with FDA and GMP sanitary standards
Genizer Lipid Extrusion Methods
Liposomes have grown as an important biomedical carrier system. One of the most critical factors influencing the performance of liposome is particle size. High-pressure homogenization, extrusion and sonication are methods for reducing liposome size. The extrusion technique is a reasonably mild and quick procedure among them.
Genizer liposome extrusion line includes jacketed liposome extruders, online extruders and hand driven liposome extruder
Genizer Jacketed Liposome Extruders:
The Genizer Jacketed Liposome Extruder utilizes a nitrogen gas cylinder to force a drug, protein or gene liposome suspension via a track-etched membrane with a predetermined pore size; generally, 5–10 passes are enough to create a sample with consistent liposome size. The Genizer Jacketed Liposome Extruders are designed to produce uniform unilamellar liposomes and lipopolyplexes with minimal dead volume.
Datasheet
